Single-Cell Analysis→

Single-cell analysis is the technical core of Jessica's thesis. High-content single-cell image analysis appears both in her G.E.R.N. role description and in her listed technical skills, and single-cell morpho-proteomic profiling is one of the three areas she names as her research focus. The principle is straightforward and the practice is not. Rather than averaging a stained population and reporting one number per condition, each cell is measured separately, so that variation within a treatment group stays visible instead of disappearing into a mean. That variation is often the finding. She has been running this since January 2025, first as an intern and from August of that year in the thesis phase. Output moves into Excel, VBA, R and SigmaPlot, wherein thousands of per-cell measurements become something comparable across conditions and timepoints. She contributed to the assay development behind it and has trained incoming interns in the workflow.