Medical Biostatistics
HiWi researcher at IMBI Freiburg under Prof. Willi Sauerbrei: EQUATOR/REMARK reporting guidelines, the STRATOS Initiative, and multivariable fractional polynomial modelling in R.
As a HiWi (student research assistant) at the Institute for Medical Biometry and Statistics (IMBI), University Medical Center Freiburg, Jessica works under Prof. Willi Sauerbrei on the reporting and analysis of observational medical studies. Her work engages directly with the EQUATOR Network reporting guidelines, including the REMARK recommendations for tumour-marker prognostic studies that Sauerbrei co-authored [1]. It also sits within the STRATOS initiative, the international collaboration Sauerbrei leads to strengthen analytical thinking and provide accessible guidance for the design and analysis of observational studies [2]. On the analytical side she applies multivariable fractional polynomial modelling in R, a flexible approach for handling continuous predictors advocated within this methodological tradition [2].
This role gives her a rigorous, guideline-first statistical foundation, an unusual and valuable complement to bench science that she brings to the modelling and reporting of her own cartilage data [1].
References
- [1] L. M. McShane, D. G. Altman, W. Sauerbrei, S. E. Taube, M. Gion, and G. M. Clark, "REporting recommendations for tumor MARKer prognostic studies (REMARK)," Nat. Clin. Pract. Urol., vol. 2, no. 8, pp. 416–422, 2005.
- [2] W. Sauerbrei, M. Abrahamowicz, D. G. Altman, S. le Cessie, and J. Carpenter, "STRengthening analytical thinking for observational studies: the STRATOS initiative," Stat. Med., vol. 33, no. 30, pp. 5413–5432, 2014.